Thursday, May 23, 2013

Length of carotid stenosis predicts peri-procedural stroke or death and restenosis in patients randomized to endovascular treatment or endarterectomy


Leo H. Bonati, Jörg Ederle, Joanna Dobson, on behalf of the CAVATAS Investigators are just about to have their paper Length of carotid stenosis predicts peri-procedural stroke or death and restenosis in patients randomized to endovascular treatment or endarterectomy published on IJS Early View. They have found that there was no difference in the occurrence of death or stroke lasting >seven-days between randomization, and 30 days after treatment between the EVT arm (23/213 patients, 10·8%: 13 nonfatal strokes, 9 fatal strokes, 1 nonstroke death) and the CEA arm (24/211 patients, 11·4%: 20 nonfatal strokes, 4 nonstroke deaths), OR 0·94 (0·52–1·72). In the entire study population, length of carotid stenosis using either definition significantly predicted the safety end-point [definition 1, i.e., using length 1 where possible and otherwise length 2: area under the ROC 0·62 (0·54–70), P = 0·008; definition 2, i.e., always using length 2: area under the ROC 0·67 (0·59–0·74), P < 0·001].

Online soon.

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